Category: SPMI

Tripping in context

Let’s say you’re sitting at a bar. You’re 1.5 drinks in: confidence blows in the sail of your diaphragm, smiles are beginning to seep from your cheeks, and the voice in your head informs your sad, previously sober-self: What the hell – I really can achieve my goals, and I really do take myself too seriously, and thank the lord for alcohol! We have to do this more often, you mopey fuck!” As GABA floats across the lanes of your head-highways your brain – rather, you – find yourself settling into a disorganized and disinhibited state of bliss. Euphoria is too complicated a word for a feeling this normal. You’re calm once more.

You’re alone in that sense. Somehow your eyes receive some brainspace from your nose, which has utterly hijacked your experience with an awful perfume smell. An older woman 2 seats over is the hare to your tortoise and the current colonizer of your nostrils. You see that she is already a walking (sitting) vessel for a bottle of wine. She orders another. Some song that your dad really likes plays on the bar speakers as you peek down at her right ankle. No mistaking the Louis Vuitton purse at her side, nor the 3 prescription bottles inside of it. Your background in medicine, druggery, and institutionalization have taught you about privacy, but being medication savvy, 3/4 of a second is all you need: notice that the pill bottles all look fresh but bear different logos: St. Paul Corner Drug, CVS, Walgreens Pharmacy. Citizen-healthy-voter you shouldn’t peek, shouldn’t judge, so you look away and try to mind your drink. Hospital-you sees the after-image of the bottles in your mind’s eye. Amphetamine, Xanax, Prozac. Yet another rich lady with a gaggle of doctors. A gaggle of neuroses, sure, and based on her medication choices she’s well aware of her own difficulties. The problem is, these medications shouldn’t be prescribed together. Any legitimate care provider would know not to prescribe an antidepressant with a benzo with a stimulant anywhere other than a college basement. The bartender asks if you want another – in the 1/2 second before answering you have a moment of sadness for all the doctors who are persecuted for prescribing. Yeah, America, blame the doctors for your kids taking adderall. Keep blaming the doctors for Prozac being ineffective. Keep blaming a bunch of debt-laden medical students for doing their best to please you. And then jump onto the next miracle cure, why don’t ya, until the next miracle cure fucks you up. And fuck wine, you think to yourself loudly. You try to remember that there’s no need to be judgmental. Even though you won’t ever relate to this lady she’s ruined your state of mind, which honestly isn’t her fault. So much for the calm.

Then, Grandma-Glamorous yells something that actually resonates: GOSH, I MEAN FOR A MAJORITY OF PEOPLE WITHOUT MAJOR DEPRESSIVE DISORDER, NONE OF THESE ANTIDEPRESSANTS WORK ANY BETTER THAN LIFESTYLE CHANGES ! THEY SAID ON THE NEWS THAT THEY’RE USING THOSE MAGIC MUSHROOMS TO MAKE THE BLUES GO AWAY, HAVEN’T YOU HEARD? DOESN’T A LITTLE WOODSTOCK SOUND MORE FUN THAN WHINING? Fearfully, you almost glance down at her purse again to see if she’s carrying any tabs. She isn’t. What is this lady onto, anyways? She’s not like you: She’s never hallucinated (recreationally or clinically), she prefers medication over lifestyle changes, she drinks like a fish, and – despite her ability to rattle off study findings – appears completely medically irreverent. She’s also upper class and has uttered words supportive of the Trump administration. You wonder if she has a therapist and realize that it doesn’t really matter. She is a consumer and she wants what she wants what she wants. So how do these folks, abusive yet wary of all things prescription, come to love magic mushrooms?

What about the clinicians who are eager to publish? Their credibility requires that they not abuse medication, and that they be less wary of prescriptions. In fact, they must plunge headfirst into pharmacological interventions despite any wariness they experience. Their patients rely on it.

What about you? The nerdy, liberal-leaning undergrad? You have seen in your own body the disastrous effects of various prescription drugs. You’ve also seen in your own body the disastrous effects of various psychedelic drugs. You’ve also seen the benefits of both of these classes of drugs. So, let’s get serious.

What do psychedelics have to offer to the everyman? To the world of clinical psychiatry? Are psychedelics like psilocybin, LSD, or MDMA beneficial for mental health? Are they harmful for mental health? How do their effects differ between younger and older people? Between men and women? Are these drugs more effective for people with diagnosed illnesses? Less effective? Dangerous? If I have major depressive disorder, and medications aren’t working for me, should I ask the young fella at the bar if he knows where to buy some shrooms?

 

 

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Amygdala regulation

Ain’t easy. Especially on low sleep. I recently stumbled upon some literature describing the relationship between the prefrontal cortex and the limbic system. Specifically it went over the connections between the prefrontal cortex and the amygdalae. Will have to come back here & post the link(s) but wanted to jot this down here, as it’s timely & highly relevant to mood disorders.

Sleep is a fickle thing & it seems that quality and duration of sleep is related to one’s ability to keep their amygdala functioning well. The absence of good quality sleep of proper duration can lead one to experience impulsiveness, out-of-control distractibility and responsiveness to irrelevant stimuli, and immense irritability. Take it from me: the vast gulf between being contented & calm or being a murderous monster can be crossed, in part, by hitting the hay.

F&c% you, NAC

And no, I don’t mean N-Acetyl Cysteine. I’m talking about the nucleus accumbens. This devilish bit of brain tissue is one that seeks for its larger meat-sack the experience of reward and short-term pleasure. To be honest the NAC isn’t the only zone related to that tendency: the frontal striatum and a few other areas are instrumental as well. To finally reach the end of the fall semester a bit bruised and battered reveals to me that my own proclivity for pressuring pleasure to pop up in the present is pretty problematic.

So the quest now is to develop skills and habits that enable the delay of gratification. In order to conduct this oversized ganglion through larger and longer movements I’ll be getting in touch with some professionals in the area who focus on this issue specifically. How exciting! Will post updates as that moves along. Here’s some soul food for any of you mind-wanderers wondering what to read about to get a sense of the issue.

Delay of gratification in childhood linked to cortical interactions with the nucleus accumbens

Frontostriatal White Matter Integrity Predicts Development of Delay of Gratification: A Longitudinal Study.

Reduced delay of gratification and effortful control among young children with autism spectrum disorders

 

A Train Without Rails

One way to really waste your time is reading on and on about mindfulness. And there is surely no end of long long long books books books offering a thousand lifetimes’ worth of answers about mindfulness. Complex, marketable, secular answers. Let’s set those answers and those long books on the shelf for now. When I was 18 years old, a scientist in Madison posed a question in the first half of a brief article. That question was Are questionnaire-based self-reports of mindfulness valid?

Now I’m 25 years old. Unresolved is ‘the questionnaire question’, but absolutely certain to me this morning was my own mindlessness. Here’s a small sample of the day’s distractions, brought to you from first-semester chemistry (via self report…validity to be determined):

 

11:15am Distracted by goal-flavored thoughts about writing a memoir of high quality, visualizing the steps associated with such a venture
11:15:30am Writing-thoughts bubbling up to account for the possibility or inevitability of memoir-thoughts
11:19am Anger-thoughts about institutional life, hot heated word-thoughts offering critiques of abusive power structures and their creations, which stemmed from thoughts about writing
11:24am What’s the best way to steal a lot of stuff from Whole Foods?
11:26am Anger-Argue thoughts about my old job, and the gross inability of my former boss to do her job (or live her live generally)

 

My intent for that 15-minute period was to simply write those thoughts that were most distracting for me. So when I noticed that my attention was unstable even for a moment, or that my mind’s eye had been occluded by some material other than coursework, I wrote down that material non-judgmentally and as it presented itself. It can be hugely valuable to understand and observe our consciousness without responding to or agreeing/disagreeing with it.

Do you have a wobbly attention span? Are you seeking more FOCUS? Go back to the shelf, pick up those conversations about secular mindfulness, and have some Mental Training™ today!

pictures, shapes and patterns <3

 

“Synesthesia” was a word that had never entered my vocabulary (or perhaps even my eyes or ears) before age 16. But the first time that the concept encroached on my consciousness it felt immediately familiar, to the point of utter, unquestioned normalcy. My sister was sitting next to me on the couch explaining that her friend at school had a bizarre tendency – an automatic habit of associating letters or numbers with colors, and quickly rattling off the sequence of colors associated with names or other words. I was struck (But Casey, you’re just blue-blue-red-green-yellow!) and a quick Wikipedia search showed both of us that I definitely had synesthesia.

2 or 3 years later during my freshman year in college I stumbled upon this documentary. If you’ve never seen it you really should- Daniel Tammet is a remarkable human being and a living window into the world of the brain. And he seems really nice too! I’d actually seen this film once in my early high school years and nearly forgotten about it. I watched this scene with Tammet’s magical description of his synesthesia on the very same day that I declared my neuroscience studies major at Macalester. It’s been 7 years and watching this still sends shivers up and down and back up my spine.

(and 7 years later, the example photo on the Wikipedia page – to roughly demonstrate the experience to non-synesthetes – is still the same! check it out below)

580px-Synesthesia.svg.png

getting the ball rolling

or, How to Turn Gloomy Nothingness into Motivation**

  1. Focus
  2. Set a sleep schedule. Stick to the sleep schedule.
  3. If all seems lost, do 100 jumping jacks and 10 push-ups
  4. Eat. Eat well.
  5. Write, but don’t write aimlessly. Don’t. Write. Aimlessly. This is not time to let loose with the pen & paper (or keyboard), or to journal about your fucking feelings, or to think up how you haven’t thought up anything yet. This is time to get regular. Write at scheduled times each day: within a few minutes after waking up, after meals, before bed.There are two genres of writing you must commit to in order to go from a state of gloomy nothingness to one of healthy motivation.5a) Write down the time you wake up (to the minute: e.g. what time exactly you stand up), what you eat/drink/ingest/intoxicate yourself with, what medications you take, and the forms of exercise you get. Writing these down each day will give you the first clear and undeniable suggestion of any bullshit you’ve been allowing yourself to get up to: sleeping in, enjoying 4 boxes of Milk Duds for breakfast several days a week, etc.
    5b) Write about your most extreme moods and prevalent thoughts. Don’t write whatever the fuck you want about them, though: don’t write aimlessly. When you write about your most extreme moods and prevalent thoughts do so in a detached way, with your intent being only to offer a memorable record to a future version of you who will be reading your day’s notes. Write about how the mood or thought came on, the content of your conscious awareness during that time, and any other relevant information. Then stop writing. Though unrewarding in the moment and tedious (combined with the genre you’ve already mastered in part 5a it will seem like you are just churning out streams of data) this style of bookkeeping will eventually form a long list of your experiences during your shittiest moments.You now have 2 small books about yourself. The first small book (writing style described in 5a), for those of us who frequently stray from our regular schedule and needs, can offer a simple and brutally honest assessment of one’s daily habits, and therefore the first steps on a route to a more motivated state of being. But when all systems are go and the vehicle is still stuck, meaning that one’s lifestyle is relatively clean but one’s outlook is still relatively filthy, the second small book (writing style described in 5b) becomes more valuable. This description of extreme experiences will offer the second, third, fourth, and fifth steps on a route towards a more specific understanding of the barriers to a more motivated state of being.

    It is extremely important for depressed people to become Writers of these two documents and to also review their writings daily.  These ever-growing documents will give you your one and only chance to more simply articulate your patterns of being and find the weak points at which to strike remaining controllable causes of your depressed mood. Should you choose to sit there and word-vomit with your writing during a depressive phase that is up to you. As for me, the mere sight and smell of my acidic unfiltered feelings spilling onto the floor, only to dry out and be-revisited over and over, doesn’t do much good. You can make your writing fun and creative in other ways: keep a journal for writing type 5a, and a separate journal for writing type 5b. Type them up into cute .pdfs and see if the extreme moods correlate with any lifestyle habits. Go buy yourself a trophy when you discover the basics. Use a special pen to write about your gloomy thoughts. Throw some stickers on that shit. Whatever floats your boat.

  6. Laugh ten times a day. No subject is off limits, just get yourself an ab workout via the giggles.
  7. Chill
  8. Meditate with supervision. Real-life human supervision.
  9. You’ve gotten this far and still feel shitty, so let me ask you this: have you told anyone that your ball has stopped rolling? Find someone to give you a push.

 

**the suggested application of these tactics comes with the assumption that you are under regular supervision and treatment by a competent psychiatric care professional who can write prescriptions. if you aren’t doing that there’s a good reason you still feel shitty.